Week 2 Case Study Pathophysiology 


All students should complete one (1) case study below.  Note: All Aquifer case studies are provided as a learning tool for students who wish to have them. 

Case 1 

A 20-year-old woman comes in concerned that she has genital herpes as she has been having unprotected sex. She does not have any lesions but wants to be tested.  

An antibody test is done and the results revealed the following: 

HSV 1 IgG type-specific antibody: < 0.90 (negative) 

HSV 2 IgG type-specific antibody: > 1.10 (positive) 

  1. How would you explain these results to her?  
  2. Can you tell if this is a recent or past infection?  
  3. Can you tell how long ago she was infected? 

Case 2

 Mr. Jones, a 45-year-old man, is concerned that he has HIV as he had unprotected receptive anal sex with a man.  

Answer the following questions.

  1. Which HIV test would be conducted first? 
  2. If he contracted HIV, how many days after exposure would be needed before the test would be positive? 
  3. Would you consider offering him PEP or PrEP, and if so, why and when?

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